If we want to talk about a local architect to replace the South Street Bridge, why not talk about H2L2?
Check out their website. Like Calatrava, they have some impressive designs:

Discovery Bridge, Columbus, Ohio

Ped Bridge in New York

Bridge in Rochester.
Rochester and
Columbus are beating us, for crying out loud! The Schuylkill--especially with Penn Connects development--deserves more than just a bunch of bland interstate bridges; it deserves
architecture!